Accelera offers a full range of bioanalytical and pharmacokinetic services to support the development of new chemical entities.
- 20+ state-of-the-art LC-MS/MS systems, including API 5000, API QTrap, QTOF, API 5500 (New!), Orbitrap (New!)
- High capacity automated systems for sample handling on multiple 96-well plates
- Watson validated LIMS system, 21 CFR part 11 compliant
- Spylog for continuous temperature monitoring of -20 °C and –80 °C sample storage.
- Fast method development for discovery compounds
- Method Development and Validation for GLP TK studies and clinical trials
- Rapid turnaround for Phase I Clinical Studies
- Bioanalytical and PK support to Phase II-III clinical studies
- PK data analysis, including population PK and PK/PD modelling, using validated software systems (e.g. Winnonlin, NONMEM)
- Logistical support for clinical sample management (sampling kits, labels, investigator manual, etc.)
- Synthesis of isotopically labelled internal standards, parent compounds and metabolites (2H, 13C, 15N, 18O)
- Metabolite profiling and identification in preclinical and clinical samples.