Developmental and Reproductive Toxicology

IN VITRO DART (non-GLP)
Accelera offers a panel of embryotoxicity in vitro models to perform early-stage reproductive studies for a rapid and affordable insight into teratogenic potential of new compounds:
  • Whole embryo culture
  • Micromass
  • Frog embryo teratogenesis assay
  • Zebrafish embryo teratogenesis assay
IN VIVO DART (ICH compliant - GLP regulated)
Accelera also offers a full in vivo regulatory testing package, with studies conducted via different routes of administration, including TK evaluation in adult animals and pups:
  • Fertily study in male and female (DRF and main studies - species: rat, mouse)
  • Embryofetal developmental toxicity study (DRF and main studies - species: rat, mouse, rabbit)
  • Pre- and postnatal developmental toxicity study (DRF and main studies - species: rat, mouse)
  • Juvenile studies (designed ad hoc) - rat, mouse.