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General Toxicology

 

Accelera offers a complete range of standard toxicology protocols designed for supporting submissions to international regulatory agencies.

Accelera conducts general toxicology studies ranging from non-GLP DRF (Dose Range Finding) up to subchronic/chronic, carcinogenicity studies for pharmaceuticals (e.g., small molecules, vaccines, and biologics), excipients and other compounds.

General toxicology studies are conducted on animals to determine the severity, duration and reversibility  of  compound-induced toxic effects, that enable to identify potential human and environmental hazards. The goal of these studies is to determine and evaluate the relationship between administered dose levels and side effects, in order to aid in selection of doses for human clinical trials.

 Quality performance and interpretation in our toxicology testing and services

With multiple test species available (including nonhuman primates), studies are overseen by Study Directors (SDs) with an average of over 100 studies and 12 years industrial experience, ensuring quality performance, interpretation, review and reporting of every aspect of your study:

  Dose Range Finding (DRF)

  Maximum Tolerated Dosing (MTD)

  Sub-chronic Toxicity

  Chronic Toxicity

Specialists in Infusion

 

Dosing by intravenous infusion has become essential to correctly evaluate the efficacy and safety of new drugs. At Accelera we have extensive experience of both continuous and intermittent infusion techniques in rodent and non-rodent species, supporting projects from in vivo research screening up to regulatory submissions.

Other Services

Reproductive Toxicology
Safety Pharmacology
Isotope Chemistry & Drug Disposition
Bioanalytical Services
Regulatory Services
Reproductive Toxicology
Safety Pharmacology
Isotope Chemistry & Drug Disposition
Bioanalytical Services
Regulatory Services

 Need information?

Please contact us if you would like to arrange a visit to your company by one of our representatives, to request a proposal, or for any more information on our services.

info@accelera.org

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