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Reproductive Toxicology

 

Accelera provides a full service in Developmental and Reproductive Toxicology (DART) for the progression of pharmaceuticals and biopharmaceuticals.
We conduct male and female fertility developmental toxicity and pre/postnatal development (PPND) studies to assess the potential effects of a test article on the full spectrum of reproduction as well as performing a range of specialised functional evaluations, including neurobehavioral testing and immunologic assays.

 In Vivo (ICH compliant – GLP regulated)

Accelera also offers a full regulated in vivo toxicological package, with studies conducted via different routes of administration, including TK evaluation in adult animals and pups:

  Fertily study in male and female (DRF and main studies – species: rat, mouse)

  Embryofetal developmental toxicity study (DRF and main studies – species: rat, mouse, rabbit)

  Pre- and postnatal developmental toxicity study (DRF and main studies – species: rat, mouse)

  Juvenile studies (designed ad hoc) – rat, mouse

In vitro DART (non-GLP)

 

Accelera offers Rat Whole Embryo Culture as an in vitro models to perform a rapid and affordable insight into teratogenic potential of new compounds or to investigate mechanisms of teratogenicity to improve extrapolation of animal data to humans.

Other Services

Safety Pharmacology
Isotope Chemistry & Drug Dispos
Bioanalytical Services
Regulatory Services
Safety Pharmacology
Isotope Chemistry & Drug Disposition
Bioanalytical Services
Regulatory Services

 Need information?

Please contact us if you would like to arrange a visit to your company by one of our representatives, to request a proposal, or for any more information on our services.

info@accelera.org

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